Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.8
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 2 capsules
Amount Per Serving
%DV
Aged Garlic Extract™†† Powder (bulb)
400 mg
**
Nattokinase (NSK-SD®)
70 mg
**
L-Theanine (Suntheanine®)
24 mg
**

Top Medical Research Studies

We assessed the effects of nattokinase crude extract (NCE) on hepatocellular carcinoma (HCC) growth in mouse models. Our findings revealed that NCE significantly improved survival rates among treated mice and resulted in decreased tumor size. The extract lowered levels of specific proteins associated with cancer progression, further indicating its potential as a treatment option. Overall, we found that NCE leads to both enhanced survival and reduced tumor growth in HCC-bearing mice.
Read More
9.5
Effective novel liver fibrosis treatment
We explored a new approach to treat liver fibrosis using a combination of a nanosized iron-locked drug generator and oral nattokinase therapy. This innovative method allows drugs to bypass barriers in the liver, ensuring they reach damaged areas effectively.

By administering iron chelator deferasirox alongside, we witnessed improved drug activation precisely in the liver, leading to significant antifibrotic effects. Remarkably, this strategy not only reversed liver fibrosis but also minimized the toxic effects of iron in the liver.

Our findings could pave the way for similar treatments targeting liver diseases in the future.
Read More

Most Useful Reviews

7.5
Effective blood pressure reduction
5 people found this helpful
I worked to lower my blood pressure as I have Polycystic Kidney Disease, but I have maintained good health overall. At my last check-up, my blood pressure was around 126/90, which concerningly indicated I might need medication. Wanting to avoid these complications, I decided to try this product after reading positive reviews and peer-reviewed studies. Initially, I took two pills daily without notable effect, but then I increased to four per day, and soon realised my readings were about 120/80. I even measured 97/76 after forgetting an evening dose! Now my blood pressure consistently sits around 110/78, and I'm pleased with the results.
Read More
9
Hypertension benefit
The results indicate that individuals with hypertension can benefit from taking Kyolic Aged Garlic to help lower blood pressure, thereby decreasing the risk of heart disease and stroke.
Read More
7.5
Reduces heart disease risk
I chose this after consulting nutritionists. It’s a high-quality garlic supplement that, with regular use, reduces the risk of cardiovascular diseases, including in women going through menopause. It's excellent for supporting the immune system and possesses antiviral and antibacterial effects.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.8
  • All Researches
9.5
Effective novel liver fibrosis treatment
We explored a new approach to treat liver fibrosis using a combination of a nanosized iron-locked drug generator and oral nattokinase therapy. This innovative method allows drugs to bypass barriers in the liver, ensuring they reach damaged areas effectively.

By administering iron chelator deferasirox alongside, we witnessed improved drug activation precisely in the liver, leading to significant antifibrotic effects. Remarkably, this strategy not only reversed liver fibrosis but also minimized the toxic effects of iron in the liver.

Our findings could pave the way for similar treatments targeting liver diseases in the future.
Read More
We assessed the effects of nattokinase crude extract (NCE) on hepatocellular carcinoma (HCC) growth in mouse models. Our findings revealed that NCE significantly improved survival rates among treated mice and resulted in decreased tumor size. The extract lowered levels of specific proteins associated with cancer progression, further indicating its potential as a treatment option. Overall, we found that NCE leads to both enhanced survival and reduced tumor growth in HCC-bearing mice.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Effective blood pressure reduction
5 people found this helpful
I worked to lower my blood pressure as I have Polycystic Kidney Disease, but I have maintained good health overall. At my last check-up, my blood pressure was around 126/90, which concerningly indicated I might need medication. Wanting to avoid these complications, I decided to try this product after reading positive reviews and peer-reviewed studies. Initially, I took two pills daily without notable effect, but then I increased to four per day, and soon realised my readings were about 120/80. I even measured 97/76 after forgetting an evening dose! Now my blood pressure consistently sits around 110/78, and I'm pleased with the results.
Read More
9
Hypertension benefit
The results indicate that individuals with hypertension can benefit from taking Kyolic Aged Garlic to help lower blood pressure, thereby decreasing the risk of heart disease and stroke.
Read More
7.5
Reduces heart disease risk
I chose this after consulting nutritionists. It’s a high-quality garlic supplement that, with regular use, reduces the risk of cardiovascular diseases, including in women going through menopause. It's excellent for supporting the immune system and possesses antiviral and antibacterial effects.
Read More
6
Quality and effectiveness
It is a quality product offering great cost-effectiveness. I'm taking it consistently as it's beneficial for vascular diseases due to its garlic ingredients.
Read More

Frequently Asked Questions

7.5
Effective blood pressure reduction
5 people found this helpful
I worked to lower my blood pressure as I have Polycystic Kidney Disease, but I have maintained good health overall. At my last check-up, my blood pressure was around 126/90, which concerningly indicated I might need medication. Wanting to avoid these complications, I decided to try this product after reading positive reviews and peer-reviewed studies. Initially, I took two pills daily without notable effect, but then I increased to four per day, and soon realised my readings were about 120/80. I even measured 97/76 after forgetting an evening dose! Now my blood pressure consistently sits around 110/78, and I'm pleased with the results.
9
Hypertension benefit
The results indicate that individuals with hypertension can benefit from taking Kyolic Aged Garlic to help lower blood pressure, thereby decreasing the risk of heart disease and stroke.
7.5
Reduces heart disease risk
I chose this after consulting nutritionists. It’s a high-quality garlic supplement that, with regular use, reduces the risk of cardiovascular diseases, including in women going through menopause. It's excellent for supporting the immune system and possesses antiviral and antibacterial effects.
9.5
Effective novel liver fibrosis treatment
We explored a new approach to treat liver fibrosis using a combination of a nanosized iron-locked drug generator and oral nattokinase therapy. This innovative method allows drugs to bypass barriers in the liver, ensuring they reach damaged areas effectively.

By administering iron chelator deferasirox alongside, we witnessed improved drug activation precisely in the liver, leading to significant antifibrotic effects. Remarkably, this strategy not only reversed liver fibrosis but also minimized the toxic effects of iron in the liver.

Our findings could pave the way for similar treatments targeting liver diseases in the future.
We assessed the effects of nattokinase crude extract (NCE) on hepatocellular carcinoma (HCC) growth in mouse models. Our findings revealed that NCE significantly improved survival rates among treated mice and resulted in decreased tumor size. The extract lowered levels of specific proteins associated with cancer progression, further indicating its potential as a treatment option. Overall, we found that NCE leads to both enhanced survival and reduced tumor growth in HCC-bearing mice.

References

  1. Sun Q, Yang W, Song Z, Lu H, Shang W, et al. Precisely Controlling the Activation of an Iron-Locked Drug Generator in the Liver Sinusoid to Enhance Barrier Penetration and Reduction of Liver Fibrosis. J Am Chem Soc. 2024;146:33784. 10.1021/jacs.4c11988
  2. Yan Y, Wang Y, Qian J, Wu S, Ji Y, et al. Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice. J Microbiol Biotechnol. 2019;29:1281. 10.4014/jmb.1812.12058
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